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Billing code

G359A — Special Single Agent Or Multi-agent Therapy Chemotherapy And/or Biologic Agent(s) With Major Toxicity That Require Frequent Monitoring And Prolonged Administration Periods And May Require Immediate Intervention By The Physician

Special high-toxicity chemotherapy

Bill G359 for chemotherapy or biologic therapy with major toxicity that needs frequent monitoring and long administration, such as high-dose methotrexate.

Watch for: It includes all assessments by any physician for the next 24 hours, plus venipuncture and line placement.

ProviderSpecialistAssistantAnaesthetistNon-anaesthetist
$105.15$0.00$0.00$0.00$0.00
Code
G359A
Description
Special Single Agent Or Multi-agent Therapy Chemotherapy And/or Biologic Agent(s) With Major Toxicity That Require Frequent Monitoring And Prolonged Administration Periods And May Require Immediate Intervention By The Physician
FHO+ basket
Not in the FHO+ base rate basket (Schedule 2 or 2B).
Effective date
Apr 1, 2025
Termination date
No end date

Explanation

Updated October 26, 2026

Special chemotherapy or biologic therapy with major toxicity that needs frequent monitoring and long administration.

What it covers

G359 is single or multi-agent chemotherapy and/or biologic therapy with major toxicity that needs frequent monitoring and prolonged administration and may need immediate physician intervention (J57).

Examples include high-dose methotrexate with folinic acid rescue, high-dose cisplatin with hydration, high-dose cyclophosphamide, ifosfamide with MESNA, biologics combined with complex chemotherapy, and bispecific antibodies (J57).

Billing rules

  • Payable only for biologic agents that are monoclonal antibodies or cytokines; blood products, insulin and vaccines are not biologic agents for this purpose (J57).
  • Includes venipuncture, any vascular access line and giving the agent(s) (J57).
  • Includes all patient assessments by any physician for 24 hours after the treatment (J57).
  • The physician must be available to intervene promptly at the start and for the whole therapy to manage immediate and delayed toxicities (J57).

Related codes: G345, G381, G390, G382, G075

Source: Schedule of Benefits (July 1, 2026), Diagnostic and Therapeutic Procedures, Injections or Infusions (Chemotherapy), page J57.

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